Food allergy| Physiology

food allergy is a medical condition where there’s an abnormal immune reaction to some food.

Now, a variety of food proteins can cause food allergies, but the most common are known as the big eight, these include proteins within milk, eggs, peanuts, tree nuts, seafood, shellfish, soy, and wheat.

Food is essential to life, and normally food doesn’t cause an allergic reaction – in fact, the process that allows for that is called oral tolerance.

Let’s see how that works. Normally, when food travels through the stomach and intestines, the proteins within them are broken down by gastric acid and proteases into tiny fragments, called oligopeptides – small strings of amino acids.

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Cluster A personality disorders| Psychology

If you were asked to describe a friend’s personality, you might describe them as generally being a creative type, or easy-going but nervous in groups.

Basically, you’re trying to summarize the personal traits that make them who they are—either how they think or how they act.

Sometimes these thought patterns or behaviors which make up a person’s personality can actually be harmful in the sense that they interfere with their day-to-day functioning in their personal life, at work, or in social settings.

If this were the case, we would say that the individual has a personality disorder.

The DSM5, or the diagnostic and statistical manual for mental disorders lists ten personality disorders that are split into three different ‘clusters’- referred to as clusters A, B, and C.

These used to be under the category “Axis 2” but that way of organizing isn’t used anymore.

Alright so cluster A personality disorders are characterized by “odd and eccentric thinking or behavior” such as believing in aliens or the Tooth Fairy at an adult age.

They include paranoid personality disorder, schizoid personality disorder, and schizotypal personality disorder, each with its own specific thought patterns and behaviors.

Paranoid personality disorder describes someone who is accusatory or generally distrustful and suspiciousness of other people without really having a reason to do so, and assumes that others will disappoint them, manipulate them, or talk about them behind their back.

Because of this, they think excessively about making sure that they have the loyalty of their friends and family.

These beliefs are so strong that they wind up affecting the way individuals act.

These people react severely if they feel that they have been lied to, or slighted in any way, which can result in their holding grudges for long periods of time.

In many ways, this behavior can totally affect the individual’s work, family life and the way they relate to those around them, creating a cycle that leads to even more paranoid behaviors, and ultimately, to social withdrawal or awkward behaviors.

Unsurprisingly, these people tend to have superficial relationships, because it’s hard to have ‘real’ bonds when you do things such as accusing your partner of cheating without having proof.

Schizoid personality disorder describes people that are aloof and avoid social interaction because they simply aren’t interested in getting to know others and not because it causes them anxiety or because they think they are possible threats.

These people even find physical contact in all forms to be less pleasurable, from sexual activity to holding hands, leading these people to be far less motivated to seek them out compared to the average individual.

In addition to generally preferring to be alone, they might also have a flat affect and emotional blunting, meaning that they tend not to show positive or negative emotions.

Finally there’s schizotypal personality disorder, which is where an individual comes across as being quirky.

These people seem overly superstitious or might engage in excessive magical thinking, which is where they might think that two completely random events are causally linked.

For example, “I got up on the left side of the bed today; therefore it’s gonna rain, because that’s what happened last time around.”

Related to this would be ideas of reference, which is a belief that everything, including innocuous events or coincidences that happens in the world, directly relate to one’s own destiny.

These people believe that they are particularly in-tune with the events around them, leads to overconfidence and a self-centered way of speaking that is socially inappropriate and can turn people off.

At the same time, they are also pretty poor at gauging how others perceive them.

Like those with schizoid personality disorder, individuals with schizotypal personality disorder tend to have few social relationships, but unlike schizoid, they usually have a strong desire to have them, but are often unable to maintain them.

A way to remember this is that those with schizoid are distant with a “D”, and those with schizotypal have magical thinking with a “T”.

There’s actually considerable overlap in diagnoses between personality disorders, even with those from the other clusters.

In fact, individuals with paranoid personality disorder often meet diagnostic criteria for schizotypal personality disorder and avoidant personality disorder, and those with schizotypal personality disorder often meet the diagnostic criteria for borderline personality disorder.

Also, all of the Cluster A personality disorders are linked to higher rates of schizophrenia, and vice versa.

Individuals who have a relative with schizophrenia are more likely to have a Cluster A personality disorder, which suggests a genetic link.

That being said, there are important differences between the personality disorders and schizophrenia itself.

For example, with paranoid schizophrenia, the paranoia is generally more intense than with paranoid personality disorder, also, people with paranoid schizophrenia may suffer from psychotic delusions, whereas those with paranoid personality disorder don’t.

There are also none of the ‘positive’ symptoms of schizophrenia, like having hallucinations or racing thoughts.

There is though, some overlap between schizoid personality disorder and some of the ‘negative’ symptoms of schizophrenia, like having a flat affect and blunted emotions.

Treatment for Cluster A disorders can be varied and difficult.

Traditional psychoanalytic treatments tend to be ineffective and might even be counter-productive, since asking these individuals to examine and confront their own contributions to their situations might cause a lot of strain.

For example, traditional talk therapies are ineffective for individuals with paranoid personality disorder because challenging the legitimacy of their beliefs is often met with even more distrust.

More effective forms of therapy seek to try to support the individual instead of challenging them, for example, by helping them to improve their understanding of social activities.

ref: Osmosis, Wikimedical

MUTATIONS OF NEW COVID19| REAL SCIENTIFIC FINDINGS


What is the mutation news in England? I explain it not with sensations or headlines, but with the scientific data we have:

What is Newly mutated COVID19 virus? What’s so different that it raised global alarm?

Newly mutated COVID19 virus has interesting mutation on B.1.1.7 Lineage Cluster mutation, which reported by CovidGenomicsUK.


What is this B.1.1.7 lineage set? We can look at the genome sequences of all living things with a “phylogenetic” family tree. We can compare the genome sequences of viruses in the family tree and see genetic diversity and new branching. These branches are given names, such as B.1.1.7 (see image)

What mutations are in this B.1.1.7 lineage set? There is a lot, see image. There are hundreds of SARSCOV2 lineages and mutations occur in each branch, this is very normal. There can be mutations in every reproductive cycle of the virus. Spike sheath protein mutations concern us the most.


For example, the N501Y mutation (ie the mutation from Asparagine to Tyrosine at the 501th position of the Spike protein) was previously able to adapt to the mouse ACE2 receptor by passing from mouse to mouse in mouse experiments. See:

https://science.sciencemag.org/content/369/6511/1603.full


In lab experiments, we know that the N501Y mutation can bind to the ACE2 receptor better. Reason: Virus Spike protein is one of the 6 important contact amino acids at the point where it attaches to ACE2. See image and source:

https://science.sciencemag.org/content/367/6485/1444.full

I will continue sharing more information as soon as possible, please share content with your friends or use it on your website with credit please.

Cocaine dependence

Cocaine, sometimes called coke, is a powerful psychoactive stimulant that alters how the brain functions—specifically, how we perceive our surroundings.

Cocaine comes from the leaves of the South American coca plant, and has been used for over a thousand years.

In modern times, it’s become a popular

“party drug” because cocaine reduces inhibitions and creates a feeling of euphoria or pleasure; this feeling lasts between fifteen and ninety minutes, depending on how the drug’s it’s administered.

Around 18 million people worldwide use cocaine, and because of its strong potential for addiction and overdose, the drug is heavily regulated in many countries.

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Body focused repetitive disorders

Body-focused repetitive disorders is an umbrella term in the DSM-5 for disorders where individuals compulsively damage their physical appearance.

These used to be classified as impulse-control disorders, but now belong in the family of obsessive-compulsive disorders.

Two of the more well-known ones are trichotillomania, which is a hair-pulling disorder, and excoriation, which is a skin-picking disorder.

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Why everyone needs extremism? Part 1 | Psychology

 Odd Andersen/AFP/Getty Images

Talking about extremism had never been so easy, it happens everywhere from religion to binge drinking.

In this article, we’re going to take a look at some examples of extremism and scientifically analyze these behaviors

Continue reading “Why everyone needs extremism? Part 1 | Psychology”

How dictatorship falls?

László Tökés is not remembered much outside Romania these days. Now 58 and the bishop of Királyhágómellék, in March 1989 he was a parish priest in Timosoara facing eviction from his church apartment. His crime was to have preached against the policy of “systemisation” – the restructuring of his country’s towns and villages ordered by the authoritarian regime of Nicolae Ceausescu.

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Seasonal affective disorder | Medicine

Recently, the DSM-5 changed the name of “seasonal affective disorder,” or SAD, to “depressive disorder with seasonal pattern.”

The new name isn’t quite as catchy as “SAD,” but it does describe the condition more precisely.

That’s because depressive disorder with seasonal pattern is not really a distinct disease, but rather depression that worsens at the same time each year, usually in the late fall and winter.

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What is COVID-19s mechanism of action in simple language? | Part 1

II researched this topic on the internet but I couldn’t find enough resources for people who don’t know medical terminology and I decided to describe it a little bit here in this topic;

Continue reading “What is COVID-19s mechanism of action in simple language? | Part 1”

Terror feelings, Death knell in mind | Part 1

Specially in these days of quarantine, I know many of us could confront with a situation called “TERROR”, but this feeling is known as depression in the belief of common people.

Continue reading “Terror feelings, Death knell in mind | Part 1”